I too experienced this, despite my gp telling me I would feel like a new woman after a few shots I felt worse. Which it could be thats making all of the physical symptoms happen. And the B12 should help as well. It's important to stick to your b12 schedule . It's my first time to take vitamin B12 in liquid form, but it's easier to eat and absorbs better than I thought. Some of those symptoms you mention also track to thyroid issues. I could go out jogging and I felt great. Now I feel like I did in my 20's. Routine test showed a B12 deficiency that was unreadable by local labs. So best bet would be to continue with that while also looking for another cause. By starting with small doses and gradually increasing them over time, drinking plenty of water both before and after the shots, and getting adequate rest, you can reduce or even eliminate any negative reactions you may experience from taking a B12 injection. 11 users are following. If any of these effects last or get worse, tell your doctor or pharmacist Has some overseas members. As you age, you produce less stomach acid, which is critical for the absorption of B12. Zero cases. Symptoms of a folate deficiency can include: numbness and tingling in the feet and hands. Your GP or nurse will give the injections. Other options include the deltoid muscle of the upper arm and the dorsogluteal site on the bottom. So pleased! Unless someone is getting B6 over 25mg a day for quite a long time, its highly unlikely for adverse effects to be seen. All rights reserved. Also, the needle needs to be long enough to reach the muscle of the person youre injecting. I can only hope that the lab repeated the test, and maybe even on a fresh sample, before you started treatment. Benefits, sources & deficiencies, 9 Hidden Dangers of Taking Health Supplements, Vitamins, Supplements and Nutrition in Pregnancy. Thanks. Theres no solid evidence that vitamin B-12 injections aid weight loss. Vitamin B12 As a general rule of thumb, take your B vitamins in the morning or with a meal. According to the medical site Drug3K, B12 injections should be stored at a stable temperature of between 59 and 86 degrees Fahrenheit. Dont store them inside a kitchen cabinet or the refrigerator. hope this answer is helpful. I hope you get the answers youre looking for too! H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h-pylori that can interfere with B12 absorption. the injection that they gave me has vitamin B-12, methione, inositol, and choline in it and was referred to as vitamin B-12 and MIC shot. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. It just goes to show that the 'B12 deficiency is unlikely in someone so young' is probably right most of the time, but not always. My son was a different person within 4 months (had 2nd worst category of villus atrophy so he was young but far gone at age 6! I was told my energy level would increase and B12 would help prevent dementia. Extreme muscle pains, tingling, tinnitus, dizziness, fatigue, twitching, cramps, actually often feel like I have the flu but no fever. If you can get to see a doctor please also ask him/her to re- check your Folate level as this and B12 help your iron to make red blood cells and to function properly. Ive started a series of weekly 1mg methyl B12 shots, and none of my symptoms have improved. It could have been worsea severe vitamin B 12 deficiency can lead to deep depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell, and more. I keep a diary of my symptoms and take other vitamins and minerals such as folic acid, iron+vitamin c and eat potassium rich foods. Hi, so I have received my 6 shots of B12. Very new to this so any advice is hugely appreciated. So all the advice and info we can read here helps to deal with the agony That is true that many doctors arent well educated about this. Sharp stabbing pains in the hands after B12 repletion is normal/expected due to nerve repair starting omce treatment begins. Based in Wales, UK. I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. My next B12 shot is due next Thursday, and about 2 weeks ago I started to feel really tired, yawning all day, needing 12 hours sleep a night. I am not a medically trained person but I've had Pernicious Anaemia (a form of B12 deficiency) for more than 46 years. If your serum B12 level was 0 then I'm guessing you feel really ill. Do NOT follow this link or you will be banned from the site! Regular provision of intravenous B12 in such circumstances is necessary for the continuation of life - its not a band-aid. Pretty dubious. Does anyone else feel worse after b12 injection. WebThis causes symptoms like muscle weakness, fatigue, appetite loss, feelings of unwellness, irritability, numbness, etc. this seems to be quit good, has good results already, and is easy to take u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all.Read More Read Less, Routine test showed a B12 deficiency that was unreadable by local labs. Had b12 low was on injections and had h pylori. do because obviously b12 medications are being used as a mere bandaid , 20yrs for some of you? Vegetarians or vegans will not be getting sufficient B12 in their diets. It's extremely unlikely such symptoms are B6 related. The side effects of not feeling well and developing acne at the age of 30 are not worth it for me, especially considering that I have not seen improvement with my migraines. WebFind out how hydroxocobalamin treats and prevents vitamin B12 deficiency anaemia, and how you'll have it. Fortunately she immediately started her on loading doses and has given her a prescription for B12 for self injection as she needs it. I was upset b/c when I returned after the first the nurse thought I'd feel cured. Mild diarrhea and/or upset stomach. Usually a dose of 0.25-0.5 mg/kg is sufficient. Contact PAS for details. People with a family history of pernicious anaemia. I don't believe the '0' results, from the '0' reported, and also the fact that everything else is utterly normal. If a person has both low b12 and low iron then their red blood cells may appear to be normal sized with normal range MCV and MCH due to the effects of the iron deficiency masking the effects of the B12 deficiency. I tend to get over excited at the thought of feeling better which then makes the disappintment when it doesnt happen much worse. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Hypophosphatemia is one of the reasons patients complain about still feeling tired after iron infusions and are feeling worse after iron infusion. Did your daughter have any abnormal hematology results? She told me that many patients tell her they feel tired as they get nearer to their B12 shot been due. Though rare, this reaction can cause muscle cramping, ?ve noticed a metallic taste after my injection. Posted and MTHFR C677T but GP and GI don't know anything about this and won't test my blood on folate, iron, magnesium, potassium, homocysteine, MMA or even my vits. Whatever the results, the complaint remains- the reason for juanpablo111 's initial visit to the walk-in clinic. I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. If its none of the things hes testing, he said its probably anxiety. Today I am hurting all over. I have had crying episodes that I did not have beforeso this vitamin injection did me little good. Some patients do feel worse before they get better. I knowwe are left in the dark Docs don't care (maybe a few do, but in generally they don't) as they are not educated well enough to understand what impact this has on patients. I have other medical conditions, and I went to a lab place to receive one to get an increase in my energy level. I dont think my actual iron levels are low and the doctor said that I am not anaemic. There is a complex interaction between folic acid, vitamin B12 and iron. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. When your body receives the B12 shot, it begins to absorb more of the nutrient than usual, which can cause a spike in energy levels. When Will I Feel Better With B12? | livestrong Look for reactions such as skin rash, swelling, a blue tint to your skin, chest tightness, etc. and Privacy Policy and steps will be taken to remove posts identified Vitamin B-12 Injection Reviews and User Ratings: Effectiveness Though rare, this reaction can cause muscle cramping, A deficiency of one may be "masked" by excess of another so the three must always be in balance. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12. An abnormal increase in red My doctor told me I could die of low B12 when mine was 100. If youre injecting a premature newborn, avoid benzyl alcohol at all cost due to the risk of gasping syndrome. Looking here on the PA forums is good, too! I am 40 years old and was tired all of the time. If it is high, it might be worth seeing what your methylmalonic acid (MMA) is doing. Cant have everything I suppose! Store the vials in a cool room. Now I I just dont know what to do that will improve my health. Hi Quinny99 I was wondering if you felt any better since your last post. Are you anybody better ? When your body receives the B12 shot, it begins to absorb more of the nutrient than usual, which can cause a spike in energy levels. Necessary cookies are absolutely essential for the website to function properly. I do recognise some of those symptoms but previous to being diagnosed I had a Thyroiditis and a bang on the head thru a collapse (now have pacemaker). So Im about to go for my first injection (as I have them once every 3 months). Some symptoms will "disappear" quite quickly whereas others may take months or even years. I went into the walk-in I just need to sort myself out as its stopping me from going to University lectures and stuff like that. When patients have suffered a B12 deficiency through a disease like pernicious anemia, then quite often the disease is only diagnosed at the end stage. Its the one that begins with an H (I cant spell it). I can't say since your gut is healing at the same timeBut as someone who had a rollercoaster in a smaller way, I can tell you that B12 is your friend and you will feel better. You'll likely feel rubbish for the next few jabs. There is no set timescale as we are all different. Also I was severely iron dificient. Everyone's different. Ive started a series of weekly 1mg methyl B12 shots, and none of my symptoms have improved. Since then it has been a real roller coaster ride. I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. I am still tired (I take iron tablets 3 times a day). Adults over 50 are at a higher risk for a B12 deficiency. If there is insufficient (or no) B12 in bloodstream, or it is not linking well with B12 at this stage, your MMA will increase in your bloodstream, and carry on increasing until B12 makes the journey and the required links. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. I have B6 toxicity, P.A. That looks good as long as you don't have digestion issues or Pernicious Anaemia whereby you cannot absorb B12 via the gut. Also my stomach that I had thought was much better before the injections is really playing up again. B12 is needed to maintain and repair the myelin sheath that protects nerves. I wouldn't want either and I feel for you with both As mentioned already, CD can go with other conditions such as thyroid, PA (low b12 can be fixed, PA requires ongoing supplements/treatment), even type 1 diabetes and other auto-immune conditions. B12 injections after Your body is damaged and will likely feel worse before you're all better. Some or all of it can be reversed and that's the good news. Its supposed to check my calcium levels, iron levels, and to see if theres any inflammation in my stomach +other things. By clicking Accept, you consent to the use of ALL the cookies. I always got some signal. Vitamin B12 or folate deficiency anaemia - Treatment - NHS However, people who follow a vegetarian or vegan diet might be prone to deficiency because plant foods don't contain vitamin B-12. The nurse seems to think its unusual to feel worse after an injection but I've now had 3 and the more pronounced. Make sure there is no air trapped inside and no blood when you pull on the syringe slightly. Stichting B12 Tekort (Dutch website with English articles). Im a lot more out of breath and experiencing dizziness. "but I do find it weird that my B12 is nonexistent and yet my RBC, MCV, and MCH are normal.". However, certain people are at an elevated risk. Thank you for all the information. Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body and your B12 levels were below the bottom of the range. I hope you are feeling better now and things are starting to settle down for you x x x. PearlH -- not sure if you'll see this, but B6 lowers FOLATE. Diet-related If your vitamin B12 deficiency is caused by a lack of the vitamin in your diet, you may be advised to take Always speak to your doctor before acting and in cases of emergency seek hope this answer is helpful. Hypophosphatemia after an iron infusion is quite rare. Patient does not provide medical advice, diagnosis or treatment. You're right Technoid. This time I felt anxious for about 10 mins that evening, tired and achy the next day, but that has been it. Doctors are now calling the gut "the second brain" so you can imagine all that goes wrong when your villi are decimated and your gut is broken down like it is in those with CD. So, don't be surprised if you mourn the loss of that identity as a "healthy person" for a while and resent the new diet and socially withdraw as you figure out the ways to get your life back and stay GF. Feeling worse after B12 Injections - Pernicious Anaemi We also use third-party cookies that help us analyze and understand how you use this website. I would respectfully ask if the B12 test could be repeated, I have learned here that B12 supplementing can alter folate levels so I wonder if your folate level being considerably above the high end of the range has masked your B12 deficiency and affected your B12 levels? There may have been other things in the mix such as Iron etc, but its highly unlikely there's a B6 toxicity issue. A lowish but witin-range result after treatment would indicate that you do have a severe B12 deficiency. If anything other than sterile saline was added, it may have been a preservative that you had reacted to. Eating bananas and trying a very healthy diet but the increase of symptoms and pain make me very, very insecure and scared. It does get better, just make sure you get the next 2 or 3 monthly top up jabsI've had to pay privately for mine as nhs seem to think a reading of 305 is okwhen it's defiantly not. They can be used intermittently and are a popular rejuvenation therapy for exhaustion, burn out, migraines and of course post-party nausea! It seems you may need high B12 supplementation and to stop any folate supplements for a while. Ive also experienced prolonged pains in my upper left part of my stomach, which happens every so often. The only difference I noticed is that my nerve endings have been more active. Im experiencing exactly the same as you. Vitamin B12 Injections Side Effects & Reactions PA Relief Sandra Hearth is the creator and writer behind "Wellbeing Port", a blog dedicated to promoting healthy living and personal wellness. There is no set timescale as we are all different. I got worse before I saw improvements. That means any excess is quickly flushed out through the urine. I thought this blood work was done AFTER the initial loading doses of B12so, yes, this result will be skewed. If the cause isn't dietary then it is an absorption problem so you need to find another way of replenishing B12 initially. i will post further progress with this drug as my treatment furthers with it. Dont fear the cases above. I hope you start to feel better soon and that you have a kind doctor who listens to you. What is the , It raises the risk for heart disease, cancer, liver damage, and stroke.